Infectious Pancreatic Necrosis

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چکیده

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Infectious Pancreatic Necrosis

Infectious pancreatic necrosis (IPN) is a viral infection primarily of trout and salmon, but the virus has also been isolated from a wide variety of other fish species. The infection is characteristically seen in trout as an acute disease causing high mortality in fry and fingerlings. However, it may also occur as a benign and inconspicuous infection (Bullock et al. 1976). Because high fish los...

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Biophysical studies of infectious pancreatic necrosis virus.

The molecular weight of infectious pancreatic necrosis virus (IPNV) has been determined by analytical ultracentrifugation and dynamic light scattering. The sedimentation coefficient of the virus was found to be 435S. The average value for molecular weight is (55 +/- 7) x 106. The virus genome consists of two segments of double-stranded RNA (molecular weights, 2.5 x 106 and 2.3 x 106), which rep...

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Thermal inactivation of infectious hematopoietic necrosis and infectious pancreatic necrosis viruses.

A plaque assay was used to follow the inactivation kinetics of infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus in cell culture media at various temperatures. Inactivation of infectious hematopoietic necrosis virus in a visceral organ slurry was compared with that in culture media.

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Physico-chemical and morphological features of infectious pancreatic necrosis virus.

Infectious pancreatic necrosis (IPN) virus has been purified and some physicochemical properties of its nucleic acid and protein moieties have been determined. The buoyant density of the virus particle in CsC1 is 1.35 g/ml; degraded particle banded at a density of 1.31 g/ml. The virus nucleic acid was found to be doublestranded, according to several different criteria, namely resistance to panc...

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Electron microscopical and biochemical characterization of infectious pancreatic necrosis virus.

An electron microscopical and biochemical examination of the properties of infectious pancreatic necrosis virus (IPN) and of its ribonucleic acid (RNA) was made. The buoyant density of IPN in CsCl was found to be 1.33 g/cm(3). Electron microscopical examination of the banded virus revealed structures similar in size (74 nm) and shape to reoviruses but lacking a characteristic inner capsid struc...

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ژورنال

عنوان ژورنال: Fish Pathology

سال: 2017

ISSN: 0388-788X,1881-7335

DOI: 10.3147/jsfp.52.177